Apoptosis biomarkers (Apaf-1, sFa s, sFa s-L, and caspase-9), albumin, and fetuin-A levels in pulmonary thromboembolic patients
نویسندگان
چکیده
منابع مشابه
What ’ s Next in Drug - Eluting SFA
VOL. 16, NO. 9 SEPTEMBER 2017 ENDOVASCULAR TODAY 73 How would you characterize the current state of drug-delivery devices available for use in the superficial femoral artery (SFA)? Our first experience with drug-delivery platforms was in the coronary arteries, where the success with drug-eluting stents (DESs) has been so significant that it is unlikely the market will revert to favoring non–dru...
متن کاملCaspase-9 and APAF-1 form an active holoenzyme.
Autocatalytic activation of initiator caspases is the link between pro-apoptotic signals and the destruction machinery of apoptosis. Activation of caspase-9, which mediates oncogene and drug-induced apoptosis, requires binding to the protein APAF-1. We found that the proteolytic activity of caspase-9 in a complex with APAF-1 is several orders of magnitude higher than that of the free enzyme. Th...
متن کاملSFA Referee Allocation Scheme
Declaration I, Nikolaos Polatidis, confirm that this work submitted for assessment is my own and is expressed in my own words. Any uses made within it of the works of other form (e.g., ideas, equations, figures, text, tables, programs) are properly acknowledged at any point of their use. A list of references employed is included. Abstract For many sports, the allocation of officials to matches ...
متن کاملRegulation of the Apaf-1-caspase-9 apoptosome.
caspase-9 apoptosome Shawn B. Bratton1 and Guy S. Salvesen2 1Division of Pharmacology and Toxicology, College of Pharmacy, and Center for Molecular and Cellular Toxicology, and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712-0125, USA 2Program in Apoptosis and Cell Death Research, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pi...
متن کاملApaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment.
Taxane derivatives such as paclitaxel elicit their antitumor effects at least in part by induction of apoptosis, but the underlying mechanisms are incompletely understood. Here, we used different cellular models with deficiencies in key regulators of apoptosis to elucidate the mechanism of paclitaxel-induced cell death. Apoptosis by paclitaxel was reported to depend on the activation of the ini...
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ژورنال
عنوان ژورنال: Disaster and Emergency Medicine Journal
سال: 2020
ISSN: 2543-5957,2451-4691
DOI: 10.5603/demj.a2020.0005